
| 2004-05 | Midget | Lasalle Vipers Minor Midget AA | 2 | 1 | 1 | 2 | 0 | - | - | 0 |
| 2005-06 | OHA-C | Blenheim | 40 | 11 | 12 | 23 | - | - | - | 102 |
| 2006-07 | OJHL-B | Sarnia | 9 | 2 | 5 | 7 | - | - | - | 16 |
| 2006-07 | OHL | Sarnia | 39 | 3 | 3 | 6 | - | - | - | 52 |
| 2007-08 | OHL | Sarnia | 66 | 25 | 13 | 38 | - | - | - | 155 |
| 2008-09 | OHL | Sarnia | 61 | 35 | 30 | 65 | 6 | - | - | 142 |
| 2009-10 | NHL | New York Islanders | 5 | 0 | 2 | 2 | -1 | 10 | 0.0% | 26 |
| 2009-10 | AHL | Bridgeport | 76 | 12 | 19 | 31 | - | - | - | 113 |
| 2010-11 | NHL | New York Islanders | 68 | 5 | 9 | 14 | -13 | 60 | 8.3% | 147 |
| 2010-11 | AHL | Bridgeport | 7 | 1 | 2 | 3 | 0 | 18 | 5.6% | 11 |
| 2011-12 | NHL | New York Islanders | 80 | 7 | 7 | 14 | -17 | 130 | 5.4% | 121 |
| 2012-13 | NHL | New York Islanders | 48 | 4 | 7 | 11 | -2 | 67 | 6.0% | 63 |
| 2013-14 | NHL | New York Islanders | 79 | 8 | 6 | 14 | -11 | 120 | 6.7% | 90 |
| 2014-15 | NHL | New York Islanders | 78 | 8 | 6 | 14 | -4 | 90 | 8.9% | 114 |
| 2015-16 | NHL | New York Islanders | 80 | 10 | 9 | 19 | 2 | 86 | 11.6% | 119 |
| 2016-17 | NHL | Toronto Maple Leafs | 82 | 5 | 4 | 9 | 0 | 66 | 7.6% | 123 |
| 2017-18 | NHL | Toronto Maple Leafs | 50 | 3 | 9 | 12 | 0 | 46 | 6.5% | 50 |
| 2018-19 | NHL | New York Islanders | 67 | 6 | 8 | 14 | 5 | 62 | 9.7% | 53 |
| 2019-20 | NHL | New York Islanders | 55 | 5 | 3 | 8 | -1 | 49 | 10.2% | 40 |
| 2020-21 | NHL | New York Islanders | 54 | 6 | 5 | 11 | -2 | 68 | 8.8% | 36 |
| 2021-22 | NHL | New York Islanders | 71 | 3 | 4 | 7 | -2 | 66 | 4.5% | 70 |
| 2022-23 | NHL | New York Islanders | 81 | 7 | 12 | 19 | 4 | 82 | 8.5% | 63 |
| 2023-24 | NHL | New York Islanders | 57 | 4 | 4 | 8 | 7 | 48 | 8.3% | 43 |
| 2024-25 | NHL | New York Islanders | 32 | 0 | 2 | 2 | -5 | 17 | 0.0% | 10 |
| NHL Totals | – | 987 | 81 | 97 | 178 | -40 | 1067 | 7.6% | 1168 | |
| AHL Totals | – | 83 | 13 | 21 | 34 | 0 | 18 | 72.2% | 124 | |
| Juniors Totals | – | 166 | 63 | 46 | 109 | 6 | - | - | 349 | |
| 2006-07 | OHL | Sarnia | 4 | 0 | 0 | 0 | 0 | 0 | 0.0% | 0 |
| 2007-08 | OHL | Sarnia | 9 | 3 | 3 | 6 | 0 | 0 | 0.0% | 16 |
| 2008-09 | OHL | Sarnia | 5 | 3 | 0 | 3 | -3 | - | - | 10 |
| 2009-10 | AHL | Bridgeport | 5 | 1 | 2 | 3 | 0 | 0 | 0.0% | 4 |
| 2012-13 | NHL | New York Islanders | 6 | 1 | 0 | 1 | 0 | 8 | 12.5% | 14 |
| 2014-15 | NHL | New York Islanders | 7 | 0 | 1 | 1 | 1 | 9 | 0.0% | 12 |
| 2015-16 | NHL | New York Islanders | 11 | 0 | 0 | 0 | -1 | 15 | 0.0% | 12 |
| 2016-17 | NHL | Toronto Maple Leafs | 6 | 0 | 2 | 2 | -2 | 4 | 0.0% | 6 |
| 2018-19 | NHL | New York Islanders | 8 | 0 | 0 | 0 | -4 | 11 | 0.0% | 0 |
| 2019-20 | NHL | New York Islanders | 22 | 5 | 1 | 6 | 0 | 28 | 17.9% | 28 |
| 2020-21 | NHL | New York Islanders | 19 | 1 | 1 | 2 | 1 | 14 | 7.1% | 43 |
| 2022-23 | NHL | New York Islanders | 6 | 1 | 0 | 1 | 0 | 4 | 25.0% | 16 |
| 2023-24 | NHL | New York Islanders | 3 | 0 | 0 | 0 | -1 | 2 | 0.0% | 16 |
| NHL Totals | – | 88 | 8 | 5 | 13 | -6 | 95 | 8.4% | 147 | |
| AHL Totals | – | 5 | 1 | 2 | 3 | 0 | 0 | - | 4 | |
| Juniors Totals | – | 18 | 6 | 3 | 9 | -3 | 0 | - | 26 | |
| Season | Opponent | Date | G | A | P | +/- | PIM | PPG | SHG | S | Shifts | TOI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Regular | @ CBJ | Apr 17 | 0 | 0 | 0 | -2 | 0 | 0 | 0 | 0 | 17 | 13:34 |
| Regular | vs WSH | Apr 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 19 | 12:33 |
| Regular | @ NJD | Apr 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 12 | 10:06 |
| Regular | @ PHI | Apr 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15 | 10:15 |
| Regular | vs NYR | Apr 10 | 0 | 0 | 0 | -1 | 0 | 0 | 0 | 2 | 17 | 13:44 |