
| 1997-98 | MTHL | Toronto Marlies | 54 | 53 | 61 | 114 | - | - | - | 42 |
| 1998-99 | OHL | Brampton | 67 | 22 | 49 | 71 | - | - | - | 18 |
| 1999-00 | OHL | Mississauga | 52 | 24 | 37 | 61 | - | - | - | 33 |
| 2000-01 | OHL | Mississauga | 15 | 7 | 23 | 30 | - | - | - | 11 |
| 2000-01 | OHL | Windsor | 41 | 36 | 50 | 86 | - | - | - | 32 |
| 2001-02 | OHL | Windsor | 27 | 19 | 26 | 45 | -5 | - | - | 16 |
| 2001-02 | OHL | Belleville | 26 | 23 | 37 | 60 | 17 | - | - | 26 |
| 2002-03 | NHL | Ottawa Senators | 33 | 7 | 14 | 21 | -3 | 65 | 10.8% | 8 |
| 2002-03 | AHL | Binghamton | 43 | 22 | 32 | 54 | -5 | 124 | 17.7% | 71 |
| 2003-04 | NHL | Ottawa Senators | 78 | 22 | 33 | 55 | 22 | 142 | 15.5% | 71 |
| 2004-05 | AHL | Binghamton | 80 | 32 | 85 | 117 | 18 | - | - | 50 |
| 2005-06 | NHL | Ottawa Senators | 68 | 19 | 71 | 90 | 23 | 156 | 12.2% | 33 |
| 2006-07 | NHL | Ottawa Senators | 67 | 34 | 53 | 87 | 19 | 162 | 21.0% | 45 |
| 2007-08 | NHL | Ottawa Senators | 76 | 34 | 58 | 92 | 26 | 210 | 16.2% | 66 |
| 2008-09 | NHL | Ottawa Senators | 82 | 32 | 41 | 73 | -14 | 246 | 13.0% | 79 |
| 2009-10 | NHL | Ottawa Senators | 60 | 23 | 34 | 57 | 0 | 165 | 13.9% | 20 |
| 2010-11 | NHL | Ottawa Senators | 62 | 21 | 36 | 57 | -7 | 188 | 11.2% | 28 |
| 2011-12 | NHL | Ottawa Senators | 80 | 34 | 50 | 84 | 11 | 232 | 14.7% | 36 |
| 2012-13 | NHL | Ottawa Senators | 5 | 2 | 3 | 5 | 3 | 12 | 16.7% | 2 |
| 2012-13 | Swiss | Rapperswil | 28 | 9 | 21 | 30 | - | - | - | 12 |
| 2013-14 | NHL | Ottawa Senators | 75 | 23 | 43 | 66 | -26 | 223 | 10.3% | 46 |
| 2014-15 | NHL | Dallas Stars | 82 | 17 | 45 | 62 | -7 | 204 | 8.3% | 28 |
| 2015-16 | NHL | Dallas Stars | 75 | 33 | 30 | 63 | 4 | 202 | 16.3% | 22 |
| 2016-17 | NHL | Dallas Stars | 68 | 15 | 35 | 50 | -18 | 149 | 10.1% | 29 |
| 2017-18 | NHL | Dallas Stars | 78 | 8 | 18 | 26 | -12 | 138 | 5.8% | 12 |
| 2018-19 | NHL | Dallas Stars | 76 | 8 | 19 | 27 | -13 | 121 | 6.6% | 29 |
| 2019-20 | NHL | Toronto Maple Leafs | 58 | 9 | 16 | 25 | -3 | 73 | 12.3% | 18 |
| 2020-21 | NHL | Toronto Maple Leafs | 54 | 10 | 20 | 30 | 3 | 81 | 12.3% | 6 |
| 2021-22 | NHL | Toronto Maple Leafs | 71 | 12 | 13 | 25 | -3 | 97 | 12.4% | 26 |
| NHL Totals | – | 1248 | 363 | 632 | 995 | 5 | 2866 | 12.7% | 604 | |
| AHL Totals | – | 123 | 54 | 117 | 171 | 13 | 124 | 43.5% | 121 | |
| Juniors Totals | – | 228 | 131 | 222 | 353 | 12 | - | - | 136 | |
| 2000-01 | OHL | Windsor | 9 | 4 | 5 | 9 | - | - | - | 10 |
| 2001-02 | OHL | Belleville | 11 | 5 | 6 | 11 | - | - | - | 18 |
| 2001-02 | AHL | Grand Rapids | 3 | 1 | 0 | 1 | - | - | - | 2 |
| 2002-03 | NHL | Ottawa Senators | 3 | 1 | 1 | 2 | 1 | 3 | 33.3% | 0 |
| 2002-03 | AHL | Binghamton | 2 | 1 | 2 | 3 | 2 | 6 | 16.7% | 4 |
| 2003-04 | NHL | Ottawa Senators | 3 | 0 | 0 | 0 | -1 | 1 | 0.0% | 2 |
| 2004-05 | AHL | Binghamton | 6 | 1 | 3 | 4 | -2 | - | - | 6 |
| 2005-06 | NHL | Ottawa Senators | 10 | 5 | 9 | 14 | -1 | 23 | 21.7% | 2 |
| 2006-07 | NHL | Ottawa Senators | 20 | 7 | 15 | 22 | 5 | 49 | 14.3% | 10 |
| 2007-08 | NHL | Ottawa Senators | 4 | 0 | 1 | 1 | -4 | 10 | 0.0% | 0 |
| 2009-10 | NHL | Ottawa Senators | 6 | 1 | 6 | 7 | -3 | 24 | 4.2% | 4 |
| 2011-12 | NHL | Ottawa Senators | 7 | 3 | 2 | 5 | 2 | 21 | 14.3% | 8 |
| 2012-13 | NHL | Ottawa Senators | 3 | 0 | 1 | 1 | -1 | 6 | 0.0% | 0 |
| 2015-16 | NHL | Dallas Stars | 13 | 5 | 8 | 13 | 0 | 34 | 14.7% | 2 |
| 2018-19 | NHL | Dallas Stars | 11 | 3 | 2 | 5 | -1 | 16 | 18.8% | 0 |
| 2019-20 | NHL | Toronto Maple Leafs | 5 | 0 | 0 | 0 | 0 | 7 | 0.0% | 9 |
| 2020-21 | NHL | Toronto Maple Leafs | 7 | 3 | 2 | 5 | 3 | 12 | 25.0% | 4 |
| 2021-22 | NHL | Toronto Maple Leafs | 5 | 0 | 1 | 1 | -2 | 6 | 0.0% | 2 |
| NHL Totals | – | 97 | 28 | 48 | 76 | -2 | 212 | 13.2% | 43 | |
| AHL Totals | – | 11 | 3 | 5 | 8 | 0 | 6 | 50.0% | 12 | |
| Juniors Totals | – | 20 | 9 | 11 | 20 | - | - | - | 28 | |
| Season | Opponent | Date | G | A | P | +/- | PIM | PPG | SHG | S | Shifts | TOI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Playoffs | vs TBL | May 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 15 | 8:13 |
| Playoffs | @ TBL | May 12 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 14 | 6:19 |
| Playoffs | vs TBL | May 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 9 | 5:50 |
| Playoffs | @ TBL | May 8 | 0 | 0 | 0 | -2 | 2 | 0 | 0 | 0 | 15 | 11:33 |
| Playoffs | @ TBL | May 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 17 | 8:23 |